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Cerebral Glucose Metabolism in Parkinson's Disease with and without Dementia Arch Neurol 49:1262-1268, Peppard,R.F.,et al, 1992 See this aricle in Pubmed Article Abstract The nondemented patients with PD showed widespread cortical glucose hypometabolism without any selective temporoparietal defects.The pattern of glucose hypometabolisn seen in the demented patients with PD resemmbled that described in patients with Alzheimer's disease;ie,there was a global decrease in glucose metabolism,with more severe abnormalities observed in the temporoparietal regions.

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